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EHMT2 Inhibition Induces Cell Death in Human Non-Small Cell Lung Cancer by Altering the Cholesterol Biosynthesis Pathway

Non-small cell lung cancer (NSCLC) is a major subtype of lung cancer. Besides genetic and environmental factors, epigenetic alterations contribute to the tumorigenesis of NSCLC. Epigenetic changes are considered key drivers of cancer initiation and progression, and altered expression and activity of...

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Detalles Bibliográficos
Autores principales: Kim, Haeun, Choi, Seo Yoon, Lim, Jinyeong, Lindroth, Anders M., Park, Yoon Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037906/
https://www.ncbi.nlm.nih.gov/pubmed/32028644
http://dx.doi.org/10.3390/ijms21031002