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A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons

Mammalian brain development critically depends on proper thyroid hormone signaling, via the TRα1 nuclear receptor. The downstream mechanisms by which TRα1 impacts brain development are currently unknown. In order to investigate these mechanisms, we used mouse genetics to induce the expression of a d...

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Detalles Bibliográficos
Autores principales: Richard, Sabine, Guyot, Romain, Rey-Millet, Martin, Prieux, Margaux, Markossian, Suzy, Aubert, Denise, Flamant, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037980/
https://www.ncbi.nlm.nih.gov/pubmed/32092701
http://dx.doi.org/10.1016/j.isci.2020.100899