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A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons
Mammalian brain development critically depends on proper thyroid hormone signaling, via the TRα1 nuclear receptor. The downstream mechanisms by which TRα1 impacts brain development are currently unknown. In order to investigate these mechanisms, we used mouse genetics to induce the expression of a d...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037980/ https://www.ncbi.nlm.nih.gov/pubmed/32092701 http://dx.doi.org/10.1016/j.isci.2020.100899 |