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Effects of A Personalized Intervention Program on the Biochemical and Hematological Profile in Community Dwelling Old Adults—The AGA@4life Intervention Model
Aging is a social and economic challenge of the highest importance and a multidisciplinary intervention seems to be a promising approach for improving the quality of life of elderly individuals. This project was designed aimed at promoting an active and healthy aging through the implementation of an...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038043/ https://www.ncbi.nlm.nih.gov/pubmed/31979121 http://dx.doi.org/10.3390/ijerph17030718 |
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author | Caseiro, Armando Rocha, Clara Silva, Ana Margarida Ferreira, Carla Silva, Isabel Clemente, Mariana Cipriano, Inês Saraiva, Marina Barreira, Rogério Azenha, Joana Loureiro, Maria Helena Martins, Anabela Pereira, Telmo |
author_facet | Caseiro, Armando Rocha, Clara Silva, Ana Margarida Ferreira, Carla Silva, Isabel Clemente, Mariana Cipriano, Inês Saraiva, Marina Barreira, Rogério Azenha, Joana Loureiro, Maria Helena Martins, Anabela Pereira, Telmo |
author_sort | Caseiro, Armando |
collection | PubMed |
description | Aging is a social and economic challenge of the highest importance and a multidisciplinary intervention seems to be a promising approach for improving the quality of life of elderly individuals. This project was designed aimed at promoting an active and healthy aging through the implementation of an intervention program based on the comprehensive geriatric assessment model (AGA@4life), focused on promoting health and wellbeing, independence and autonomy, mobility, and social inclusion. A non-randomized interventional study was designed to evaluate the effect of only a dietetic and nutritional approach (control group (CG)) and the combination of a tailored exercise program and a dietetic and nutritional approach (intervention group (IG)) in the biochemical and hematological profile of older adults in the framework of AGA@4life. The 34 participants enrolled, aged 65 years or over, were subject to a thorough baseline (T0) multidisciplinary diagnostic evaluation, including the gathering of clinical information and a battery of biochemical and hematological determinations, and reevaluated after eight weeks of intervention (T1). Between T0 and T1, an increase in albumin and total proteins serum levels were observed in both groups (p < 0.01); the hematological profile in CG and IG showed an increase in red cell count and hemoglobin (p < 0.05). In IG, an increase of HDL cholesterol (p < 0.001) and a decrease of triglycerides (p = 0.001) were still observed. The AGA@4life multidisciplinary intervention improved the hematological and biochemical profile of old adults, potentially contributing to delay the development of several aging comorbidities and increase the quality of life of participants. |
format | Online Article Text |
id | pubmed-7038043 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70380432020-03-10 Effects of A Personalized Intervention Program on the Biochemical and Hematological Profile in Community Dwelling Old Adults—The AGA@4life Intervention Model Caseiro, Armando Rocha, Clara Silva, Ana Margarida Ferreira, Carla Silva, Isabel Clemente, Mariana Cipriano, Inês Saraiva, Marina Barreira, Rogério Azenha, Joana Loureiro, Maria Helena Martins, Anabela Pereira, Telmo Int J Environ Res Public Health Article Aging is a social and economic challenge of the highest importance and a multidisciplinary intervention seems to be a promising approach for improving the quality of life of elderly individuals. This project was designed aimed at promoting an active and healthy aging through the implementation of an intervention program based on the comprehensive geriatric assessment model (AGA@4life), focused on promoting health and wellbeing, independence and autonomy, mobility, and social inclusion. A non-randomized interventional study was designed to evaluate the effect of only a dietetic and nutritional approach (control group (CG)) and the combination of a tailored exercise program and a dietetic and nutritional approach (intervention group (IG)) in the biochemical and hematological profile of older adults in the framework of AGA@4life. The 34 participants enrolled, aged 65 years or over, were subject to a thorough baseline (T0) multidisciplinary diagnostic evaluation, including the gathering of clinical information and a battery of biochemical and hematological determinations, and reevaluated after eight weeks of intervention (T1). Between T0 and T1, an increase in albumin and total proteins serum levels were observed in both groups (p < 0.01); the hematological profile in CG and IG showed an increase in red cell count and hemoglobin (p < 0.05). In IG, an increase of HDL cholesterol (p < 0.001) and a decrease of triglycerides (p = 0.001) were still observed. The AGA@4life multidisciplinary intervention improved the hematological and biochemical profile of old adults, potentially contributing to delay the development of several aging comorbidities and increase the quality of life of participants. MDPI 2020-01-22 2020-02 /pmc/articles/PMC7038043/ /pubmed/31979121 http://dx.doi.org/10.3390/ijerph17030718 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Caseiro, Armando Rocha, Clara Silva, Ana Margarida Ferreira, Carla Silva, Isabel Clemente, Mariana Cipriano, Inês Saraiva, Marina Barreira, Rogério Azenha, Joana Loureiro, Maria Helena Martins, Anabela Pereira, Telmo Effects of A Personalized Intervention Program on the Biochemical and Hematological Profile in Community Dwelling Old Adults—The AGA@4life Intervention Model |
title | Effects of A Personalized Intervention Program on the Biochemical and Hematological Profile in Community Dwelling Old Adults—The AGA@4life Intervention Model |
title_full | Effects of A Personalized Intervention Program on the Biochemical and Hematological Profile in Community Dwelling Old Adults—The AGA@4life Intervention Model |
title_fullStr | Effects of A Personalized Intervention Program on the Biochemical and Hematological Profile in Community Dwelling Old Adults—The AGA@4life Intervention Model |
title_full_unstemmed | Effects of A Personalized Intervention Program on the Biochemical and Hematological Profile in Community Dwelling Old Adults—The AGA@4life Intervention Model |
title_short | Effects of A Personalized Intervention Program on the Biochemical and Hematological Profile in Community Dwelling Old Adults—The AGA@4life Intervention Model |
title_sort | effects of a personalized intervention program on the biochemical and hematological profile in community dwelling old adults—the aga@4life intervention model |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038043/ https://www.ncbi.nlm.nih.gov/pubmed/31979121 http://dx.doi.org/10.3390/ijerph17030718 |
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