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Knockdown of Atg7 Induces Nuclear-LC3 Dependent Apoptosis and Augments Chemotherapy in Colorectal Cancer Cells

Autophagy is a catabolic process that enables cells to degrade obsolete content and refuel energy depots. In colorectal cancer (CRC) autophagy has been shown to promote tumorigenesis through energy delivery in the condition of uncontrolled proliferation. With this study, we aimed at evaluating wheth...

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Detalles Bibliográficos
Autores principales: Scherr, Anna-Lena, Jassowicz, Adam, Pató, Anna, Elssner, Christin, Ismail, Lars, Schmitt, Nathalie, Hoffmeister, Paula, Neukirch, Lasse, Gdynia, Georg, Goeppert, Benjamin, Schulze-Bergkamen, Henning, Jäger, Dirk, Köhler, Bruno Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038172/
https://www.ncbi.nlm.nih.gov/pubmed/32046105
http://dx.doi.org/10.3390/ijms21031099