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Knockdown of Atg7 Induces Nuclear-LC3 Dependent Apoptosis and Augments Chemotherapy in Colorectal Cancer Cells
Autophagy is a catabolic process that enables cells to degrade obsolete content and refuel energy depots. In colorectal cancer (CRC) autophagy has been shown to promote tumorigenesis through energy delivery in the condition of uncontrolled proliferation. With this study, we aimed at evaluating wheth...
Autores principales: | Scherr, Anna-Lena, Jassowicz, Adam, Pató, Anna, Elssner, Christin, Ismail, Lars, Schmitt, Nathalie, Hoffmeister, Paula, Neukirch, Lasse, Gdynia, Georg, Goeppert, Benjamin, Schulze-Bergkamen, Henning, Jäger, Dirk, Köhler, Bruno Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038172/ https://www.ncbi.nlm.nih.gov/pubmed/32046105 http://dx.doi.org/10.3390/ijms21031099 |
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