A Randomized Controlled Trial of Three- versus Five-Day Artemether-Lumefantrine Regimens for Treatment of Uncomplicated Plasmodium falciparum Malaria in Pregnancy in Africa

Artemether-lumefantrine antimalarial efficacy in pregnancy could be compromised by reduced drug exposure. Population-based simulations suggested that therapeutic efficacy would be improved if the treatment duration was increased. We assessed the efficacy, tolerability, and pharmacokinetics of an ext...

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Detalles Bibliográficos
Autores principales: Onyamboko, Marie A., Hoglund, Richard M., Lee, Sue J., Kabedi, Charlie, Kayembe, Daddy, Badjanga, Benjamin B., Turner, Gareth D. H., Jackson, Nikky V., Tarning, Joel, McGready, Rose, Nosten, Francois, White, Nicholas J., Day, Nicholas P. J., Fanello, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038309/
https://www.ncbi.nlm.nih.gov/pubmed/31818818
http://dx.doi.org/10.1128/AAC.01140-19

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