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Discovering weaker genetic associations guided by known associations

BACKGROUND: The current understanding of the genetic basis of complex human diseases is that they are caused and affected by many common and rare genetic variants. A considerable number of the disease-associated variants have been identified by Genome Wide Association Studies, however, they can expl...

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Detalles Bibliográficos
Autores principales: Wang, Haohan, Vanyukov, Michael M., Xing, Eric P., Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038505/
https://www.ncbi.nlm.nih.gov/pubmed/32093702
http://dx.doi.org/10.1186/s12920-020-0667-4