ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is a malignancy characterized by metabolic reprogramming. ABAT and ALDH6A1 are metabolic enzymes. In this study, we aim to investigate the associations of ABAT and ALDH6A1 with the malignancy of ccRCC cells. METHODS: The gene expression levels of A...

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Detalles Bibliográficos
Autores principales: Lu, Jun, Chen, Zhan, Zhao, Hu, Dong, Huiyue, Zhu, Ling, Zhang, Yi, Wang, Jie, Zhu, Hehuan, Cui, Qiang, Qi, Chuang, Wang, Shuiliang, Chen, Shushang, Shao, Jichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038561/
https://www.ncbi.nlm.nih.gov/pubmed/32093682
http://dx.doi.org/10.1186/s12967-020-02268-1

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