A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer

The characterization of mutational processes in terms of their signatures of activity relies mostly on the assumption that mutations in a given cancer genome are independent of one another. Recently, it was discovered that certain segments of mutations, termed processive groups, occur on the same DN...

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Detalles Bibliográficos
Autores principales: Sason, Itay, Wojtowicz, Damian, Robinson, Welles, Leiserson, Mark D.M., Przytycka, Teresa M., Sharan, Roded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038582/
https://www.ncbi.nlm.nih.gov/pubmed/32088392
http://dx.doi.org/10.1016/j.isci.2020.100900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038582/
https://www.ncbi.nlm.nih.gov/pubmed/32088392
http://dx.doi.org/10.1016/j.isci.2020.100900

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