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A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer
The characterization of mutational processes in terms of their signatures of activity relies mostly on the assumption that mutations in a given cancer genome are independent of one another. Recently, it was discovered that certain segments of mutations, termed processive groups, occur on the same DN...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038582/ https://www.ncbi.nlm.nih.gov/pubmed/32088392 http://dx.doi.org/10.1016/j.isci.2020.100900 |