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Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition

Staufen1 (STAU1) is a dsRNA binding protein mediating mRNA transport and localization, translational control and STAU1-mediated mRNA decay (SMD). The STAU1 binding site (SBS) within human ADP-ribosylation factor1 (ARF1) 3′UTR binds STAU1 and this downregulates ARF1 cytoplasmic mRNA levels by SMD. Ho...

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Detalles Bibliográficos
Autores principales:	Yadav, Deepak Kumar, Zigáčková, Dagmar, Zlobina, Maria, Klumpler, Tomáš, Beaumont, Christelle, Kubíčková, Monika, Vaňáčová, Štěpánka, Lukavsky, Peter J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038937/ https://www.ncbi.nlm.nih.gov/pubmed/31875226 http://dx.doi.org/10.1093/nar/gkz1163

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