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Pre-folded structures govern folding pathways of human telomeric G-quadruplexes

Understanding the mechanism by which biological macromolecules fold into their functional native conformations represents a problem of fundamental interest. DNA oligonucleotides derived from human telomeric repeat d[TAGGG(TTAGGG)(3)] and d[TAGGG(TTAGGG)(3)TT] fold into G-quadruplexes through diverse...

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Detalles Bibliográficos
Autores principales:	Frelih, Tjaša, Wang, Baifan, Plavec, Janez, Šket, Primož
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038944/ https://www.ncbi.nlm.nih.gov/pubmed/31950178 http://dx.doi.org/10.1093/nar/gkz1235

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