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Dynamics of DNA nicking and unwinding by the RepC–PcrA complex

The rolling-circle replication is the most common mechanism for the replication of small plasmids carrying antibiotic resistance genes in Gram-positive bacteria. It is initiated by the binding and nicking of double-stranded origin of replication by a replication initiator protein (Rep). Duplex unwin...

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Detalles Bibliográficos
Autores principales: Carrasco, Carolina, Pastrana, Cesar L, Aicart-Ramos, Clara, Leuba, Sanford H, Khan, Saleem A, Moreno-Herrero, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038956/
https://www.ncbi.nlm.nih.gov/pubmed/31930301
http://dx.doi.org/10.1093/nar/gkz1200