tRNA 2′-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila

2′-O-Methylation (Nm) represents one of the most common RNA modifications. Nm affects RNA structure and function with crucial roles in various RNA-mediated processes ranging from RNA silencing, translation, self versus non-self recognition to viral defense mechanisms. Here, we identify two Nm methyl...

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Detalles Bibliográficos
Autores principales: Angelova, Margarita T, Dimitrova, Dilyana G, Da Silva, Bruno, Marchand, Virginie, Jacquier, Caroline, Achour, Cyrinne, Brazane, Mira, Goyenvalle, Catherine, Bourguignon-Igel, Valérie, Shehzada, Salman, Khouider, Souraya, Lence, Tina, Guerineau, Vincent, Roignant, Jean-Yves, Antoniewski, Christophe, Teysset, Laure, Bregeon, Damien, Motorin, Yuri, Schaefer, Matthias R, Carré, Clément
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038984/
https://www.ncbi.nlm.nih.gov/pubmed/31943105
http://dx.doi.org/10.1093/nar/gkaa002

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