Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity

Steroid hormones are pivotal modulators of pathophysiological processes in many organs, where they interact with nuclear receptors to regulate gene transcription. However, our understanding of hormone action at the single cell level remains incomplete. Here, we focused on estrogen stimulation of the...

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Detalles Bibliográficos
Autores principales: Stossi, Fabio, Dandekar, Radhika D, Mancini, Maureen G, Gu, Guowei, Fuqua, Suzanne A W, Nardone, Agostina, De Angelis, Carmine, Fu, Xiaoyong, Schiff, Rachel, Bedford, Mark T, Xu, Wei, Johansson, Hans E, Stephan, Clifford C, Mancini, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039002/
https://www.ncbi.nlm.nih.gov/pubmed/31930333
http://dx.doi.org/10.1093/nar/gkz1172

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