Cargando…

Elevated expression of exosomal microRNA-21 as a potential biomarker for the early diagnosis of pancreatic cancer using a tethered cationic lipoplex nanoparticle biochip

Pancreatic cancer (PC) has a poor prognosis due to the lack of effective molecular biomarkers for early diagnosis. Recent studies have investigated the use of exosomal microRNAs (exmiRs) as diagnostic biomarkers in cancer. The present study examined exmiR-21, exmiR-10b and exmiR-212-3p expression in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pu, Xiaofan, Ding, Guoping, Wu, Mingjie, Zhou, Senhao, Jia, Shengnan, Cao, Liping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039151/ https://www.ncbi.nlm.nih.gov/pubmed/32194703 http://dx.doi.org/10.3892/ol.2020.11302

Ejemplares similares

Non-invasive Detection of Exosomal MicroRNAs via Tethered Cationic Lipoplex Nanoparticles (tCLN) Biochip for Lung Cancer Early Detection
por: Liu, Chang, et al.
Publicado: (2020)

Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer
por: Wu, Yun, et al.
Publicado: (2013)

Trichain cationic lipids: the potential of their lipoplexes for gene delivery
por: Kudsiova, Laila, et al.
Publicado: (2019)

Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma
por: Wang, Xinmei, et al.
Publicado: (2018)

Down-expression of CD36 in pancreatic adenocarcinoma and its correlation with clinicopathological features and prognosis
por: Jia, Shengnan, et al.
Publicado: (2018)

Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways
por: Jia, Shengnan, et al.
Publicado: (2019)

Probing the in vitro mechanism of action of cationic lipid/DNA lipoplexes at a nanometric scale
por: Le Bihan, Olivier, et al.
Publicado: (2011)

Analysis of serum exosomal microRNAs and clinicopathologic features of patients with pancreatic adenocarcinoma
por: Que, Risheng, et al.
Publicado: (2013)

Controlled pDNA Release in Gemini Cationic Lipoplexes by Femtosecond Laser Irradiation of Gold Nanostars
por: Sánchez-Arribas, Natalia, et al.
Publicado: (2021)

PEGylation and folic-acid functionalization of cationic lipoplexes—Improved nucleic acid transfer into cancer cells
por: Hoffmann, Marco, et al.
Publicado: (2022)

Tetherin is an exosomal tether
por: Edgar, James R, et al.
Publicado: (2016)

Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes
por: Hattori, Yoshiyuki, et al.
Publicado: (2022)

Microchips, Microarrays, Biochips and Nanochips - Personal Laboratories for the 21st Century
por: Kricka, Larry J
Publicado: (2000)

Magnetic nanochain integrated microfluidic biochips
por: Xiong, Qirong, et al.
Publicado: (2018)

An elevated expression of serum exosomal microRNA-191, − 21, −451a of pancreatic neoplasm is considered to be efficient diagnostic marker
por: Goto, Takuma, et al.
Publicado: (2018)

High Expression of P38α and Preoperative Carbohydrate Antigen 19-9 Indicate Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma
por: Chen, Jionghuang, et al.
Publicado: (2018)

mRNA Lipoplexes with Cationic and Ionizable α-Amino-lipophosphonates: Membrane Fusion, Transfection, mRNA Translation and Conformation
por: Akhter, Sohail, et al.
Publicado: (2022)

Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes
por: Hattori, Yoshiyuki, et al.
Publicado: (2021)

Biochips: technology and applications
por: Xing, Wan-Li, et al.
Publicado: (2003)

microRNA Detection via Nanostructured Biochips for Early Cancer Diagnostics
por: Martino, Sara, et al.
Publicado: (2023)

Expression of DEK in pancreatic cancer and its correlation with clinicopathological features and prognosis
por: Zhao, Ting, et al.
Publicado: (2019)

Effect of the combination of cationic lipid and phospholipid on gene-knockdown using siRNA lipoplexes in breast tumor cells and mouse lungs
por: Hattori, Yoshiyuki, et al.
Publicado: (2023)

Inhibition of breast cancer with transdermal tamoxifen-encapsulated lipoplex
por: Lin, Yu-Ling, et al.
Publicado: (2016)

Liposome-coated lipoplex–based carrier for antisense oligonucleotides
por: Wyrozumska, Paulina, et al.
Publicado: (2014)

Implication of Biochips in Tuberculosis Diagnostics
por: Zimenkov,, D.V., et al.
Publicado: (2011)

Biochip Platforms for DNA Diagnostics
por: Deisingh, Anil K., et al.
Publicado: (2009)

DNA Vaccine Administered by Cationic Lipoplexes or by In Vivo Electroporation Induces Comparable Antibody Responses against SARS-CoV-2 in Mice
por: Peletta, Allegra, et al.
Publicado: (2021)

Combined Inhibition of FOSL-1 and YAP Using siRNA-Lipoplexes Reduces the Growth of Pancreatic Tumor
por: Diego-González, Lara, et al.
Publicado: (2022)

Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profile in Pancreatic Cancer Derived Exosomes Treated Dendritic Cells by Microarray Analysis
por: Chen, Jionghuang, et al.
Publicado: (2018)

BxPC-3-Derived Small Extracellular Vesicles Induce FOXP3+ Treg through ATM-AMPK-Sirtuins-Mediated FOXOs Nuclear Translocations
por: Shen, Tao, et al.
Publicado: (2020)

Exploring the Correlation Between Lipid Packaging in Lipoplexes and Their Transfection Efficacy
por: Moghaddam, Behfar, et al.
Publicado: (2011)

Interaction of Lipoplex with Albumin Enhances Gene Expression in Hepatitis Mice
por: Yoshikawa, Naoki, et al.
Publicado: (2020)

A molecular view on the escape of lipoplexed DNA from the endosome
por: Bruininks, Bart MH, et al.
Publicado: (2020)

The distinct role of CD73 in the progression of pancreatic cancer
por: Zhou, Liangjing, et al.
Publicado: (2019)

Down-regulation of miR-30a-5p is Associated with Poor Prognosis and Promotes Chemoresistance of Gemcitabine in Pancreatic Ductal Adenocarcinoma
por: Zhou, Liangjing, et al.
Publicado: (2019)

Design and Testing of Digital Microfluidic Biochips
por: Zhao, Yang, et al.
Publicado: (2013)

Effect of ionic strength and presence of serum on lipoplexes structure monitorized by FRET
por: Madeira, Catarina, et al.
Publicado: (2008)

Development of siRNA lipoplexes for intracellular delivery in lung cancer cells
por: Khatri, N., et al.
Publicado: (2012)

Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids
por: Buck, Jonas, et al.
Publicado: (2020)

Fate of Tableted Freeze-Dried siRNA Lipoplexes in Gastrointestinal Environment
por: Rehman, Asad Ur, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3c9gl1rag0n03d35on1j107rj6