ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer

How the distinct lipid composition of organelles is determined and maintained is still poorly understood. In this issue, Du et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201905162) show that the lipid transfer protein ORP5 functions at ER–LD contact sites, regulating lipid droplet levels o...

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Detalles Bibliográficos
Autores principales: Renne, Mike F., Emerling, Brooke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039197/
https://www.ncbi.nlm.nih.gov/pubmed/31868890
http://dx.doi.org/10.1083/jcb.201912010
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author Renne, Mike F.
Emerling, Brooke M.
author_facet Renne, Mike F.
Emerling, Brooke M.
author_sort Renne, Mike F.
collection PubMed
description How the distinct lipid composition of organelles is determined and maintained is still poorly understood. In this issue, Du et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201905162) show that the lipid transfer protein ORP5 functions at ER–LD contact sites, regulating lipid droplet levels of phosphatidylserine and phosphatidylinositol-4-phosphate.
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spelling pubmed-70391972020-07-06 ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer Renne, Mike F. Emerling, Brooke M. J Cell Biol Commentaries How the distinct lipid composition of organelles is determined and maintained is still poorly understood. In this issue, Du et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201905162) show that the lipid transfer protein ORP5 functions at ER–LD contact sites, regulating lipid droplet levels of phosphatidylserine and phosphatidylinositol-4-phosphate. Rockefeller University Press 2019-12-23 /pmc/articles/PMC7039197/ /pubmed/31868890 http://dx.doi.org/10.1083/jcb.201912010 Text en © 2019 Renne and Emerling http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Renne, Mike F.
Emerling, Brooke M.
ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer
title ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer
title_full ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer
title_fullStr ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer
title_full_unstemmed ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer
title_short ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer
title_sort orp5 regulates pi(4)p on the lipid droplet: novel players on the monolayer
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039197/
https://www.ncbi.nlm.nih.gov/pubmed/31868890
http://dx.doi.org/10.1083/jcb.201912010
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