Cargando…
ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer
How the distinct lipid composition of organelles is determined and maintained is still poorly understood. In this issue, Du et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201905162) show that the lipid transfer protein ORP5 functions at ER–LD contact sites, regulating lipid droplet levels o...
Autores principales: | Renne, Mike F., Emerling, Brooke M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039197/ https://www.ncbi.nlm.nih.gov/pubmed/31868890 http://dx.doi.org/10.1083/jcb.201912010 |
Ejemplares similares
-
ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets
por: Du, Ximing, et al.
Publicado: (2019) -
ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER–mitochondria contact sites
por: Guyard, Valentin, et al.
Publicado: (2022) -
Crucial Players for Inter-Organelle Communication: PI5P4Ks and Their Lipid Product PI-4,5-P(2) Come to the Surface
por: Ravi, Archna, et al.
Publicado: (2022) -
ORP8 acts as a lipophagy receptor to mediate lipid droplet turnover
por: Pu, Maomao, et al.
Publicado: (2022) -
Reconstitution of ORP-mediated lipid exchange process coupled to PI(4)P metabolism
por: Fuggetta, Nicolas, et al.
Publicado: (2023)