SNX27–retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis

A variety of metastatic cancer cells use actin-rich membrane protrusions, known as invadopodia, for efficient ECM degradation, which involves trafficking of proteases from intracellular compartments to these structures. Here, we demonstrate that in the metastatic breast cancer cell line MDA-MB-231,...

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Detalles Bibliográficos
Autores principales: Sharma, Priyanka, Parveen, Sameena, Shah, Lekha V., Mukherjee, Madhumita, Kalaidzidis, Yannis, Kozielski, Anthony J., Rosato, Roberto, Chang, Jenny C., Datta, Sunando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039210/
https://www.ncbi.nlm.nih.gov/pubmed/31820782
http://dx.doi.org/10.1083/jcb.201812098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039210/
https://www.ncbi.nlm.nih.gov/pubmed/31820782
http://dx.doi.org/10.1083/jcb.201812098

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