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SNX27–retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis
A variety of metastatic cancer cells use actin-rich membrane protrusions, known as invadopodia, for efficient ECM degradation, which involves trafficking of proteases from intracellular compartments to these structures. Here, we demonstrate that in the metastatic breast cancer cell line MDA-MB-231,...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039210/ https://www.ncbi.nlm.nih.gov/pubmed/31820782 http://dx.doi.org/10.1083/jcb.201812098 |