Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires

Antibodies from B-cell clonal lineages share sequence and structural properties as well as epitope specificity. Clonally unrelated antibodies can similarly share sequence and specificity properties and are said to be convergent. Convergent antibody responses against several antigens have been descri...

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Detalles Bibliográficos
Autores principales: Hsiao, Yi-Chun, Chen, Ying-Jiun J., Goldstein, Leonard D., Wu, Jia, Lin, Zhonghua, Schneider, Kellen, Chaudhuri, Subhra, Antony, Aju, Bajaj Pahuja, Kanika, Modrusan, Zora, Seshasayee, Dhaya, Seshagiri, Somasekar, Hötzel, Isidro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039645/
https://www.ncbi.nlm.nih.gov/pubmed/32041466
http://dx.doi.org/10.1080/19420862.2020.1722541

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