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Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome

Methylation of histone H3K4 is a hallmark of actively transcribed genes that depends on mono-ubiquitination of histone H2B (H2B-Ub). H3K4 methylation in yeast is catalyzed by Set1, the methyltransferase subunit of COMPASS. We report here the cryo-EM structure of a six-protein core COMPASS subcomplex...

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Detalles Bibliográficos
Autores principales:	Worden, Evan J, Zhang, Xiangbin, Wolberger, Cynthia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039682/ https://www.ncbi.nlm.nih.gov/pubmed/31922488 http://dx.doi.org/10.7554/eLife.53199

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