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Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution

Breast cancer (BC) is the most common malignancy in women. We retrieved medical records from >2,000 Chilean BC patients over the 1997–2018 period. The objective was to assess changes in clinical presentation or prognosis of our patients throughout these 20 years of practice. Although most variabl...

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Autores principales: Maiz, Cristóbal, Silva, Fernando, Domínguez, Francisco, Galindo, Héctor, Camus, Mauricio, León, Augusto, Oddó, David, Villarroel, Alejandra, Razmilic, Dravna, Navarro, María Elena, Medina, Lidia, Merino, Tomás, Vines, Eugenio, Peña, José, Maldonado, Daniela, Pinto, Mauricio P., Acevedo, Francisco, Sánchez, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039691/
https://www.ncbi.nlm.nih.gov/pubmed/32104207
http://dx.doi.org/10.3332/ecancer.2020.1005
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author Maiz, Cristóbal
Silva, Fernando
Domínguez, Francisco
Galindo, Héctor
Camus, Mauricio
León, Augusto
Oddó, David
Villarroel, Alejandra
Razmilic, Dravna
Navarro, María Elena
Medina, Lidia
Merino, Tomás
Vines, Eugenio
Peña, José
Maldonado, Daniela
Pinto, Mauricio P.
Acevedo, Francisco
Sánchez, César
author_facet Maiz, Cristóbal
Silva, Fernando
Domínguez, Francisco
Galindo, Héctor
Camus, Mauricio
León, Augusto
Oddó, David
Villarroel, Alejandra
Razmilic, Dravna
Navarro, María Elena
Medina, Lidia
Merino, Tomás
Vines, Eugenio
Peña, José
Maldonado, Daniela
Pinto, Mauricio P.
Acevedo, Francisco
Sánchez, César
author_sort Maiz, Cristóbal
collection PubMed
description Breast cancer (BC) is the most common malignancy in women. We retrieved medical records from >2,000 Chilean BC patients over the 1997–2018 period. The objective was to assess changes in clinical presentation or prognosis of our patients throughout these 20 years of practice. Although most variables did not display significant variations, we observed a progressive increase in stage IV BC over this period. Our data showed that tumour stage III/IV or HER2-enriched subtype tumours were associated with poorer prognosis. In contrast, we found that patients diagnosed by mammography had better overall survival. We speculate that better screenings and more sensitive imaging could explain the unexpected rise in stage IV cases. Our results support mammography screenings as an effective measure to reduce BC-related mortality.
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spelling pubmed-70396912020-02-26 Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution Maiz, Cristóbal Silva, Fernando Domínguez, Francisco Galindo, Héctor Camus, Mauricio León, Augusto Oddó, David Villarroel, Alejandra Razmilic, Dravna Navarro, María Elena Medina, Lidia Merino, Tomás Vines, Eugenio Peña, José Maldonado, Daniela Pinto, Mauricio P. Acevedo, Francisco Sánchez, César Ecancermedicalscience Short Communication Breast cancer (BC) is the most common malignancy in women. We retrieved medical records from >2,000 Chilean BC patients over the 1997–2018 period. The objective was to assess changes in clinical presentation or prognosis of our patients throughout these 20 years of practice. Although most variables did not display significant variations, we observed a progressive increase in stage IV BC over this period. Our data showed that tumour stage III/IV or HER2-enriched subtype tumours were associated with poorer prognosis. In contrast, we found that patients diagnosed by mammography had better overall survival. We speculate that better screenings and more sensitive imaging could explain the unexpected rise in stage IV cases. Our results support mammography screenings as an effective measure to reduce BC-related mortality. Cancer Intelligence 2020-01-23 /pmc/articles/PMC7039691/ /pubmed/32104207 http://dx.doi.org/10.3332/ecancer.2020.1005 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Maiz, Cristóbal
Silva, Fernando
Domínguez, Francisco
Galindo, Héctor
Camus, Mauricio
León, Augusto
Oddó, David
Villarroel, Alejandra
Razmilic, Dravna
Navarro, María Elena
Medina, Lidia
Merino, Tomás
Vines, Eugenio
Peña, José
Maldonado, Daniela
Pinto, Mauricio P.
Acevedo, Francisco
Sánchez, César
Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution
title Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution
title_full Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution
title_fullStr Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution
title_full_unstemmed Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution
title_short Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution
title_sort mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a university health institution
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039691/
https://www.ncbi.nlm.nih.gov/pubmed/32104207
http://dx.doi.org/10.3332/ecancer.2020.1005
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