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Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution
Breast cancer (BC) is the most common malignancy in women. We retrieved medical records from >2,000 Chilean BC patients over the 1997–2018 period. The objective was to assess changes in clinical presentation or prognosis of our patients throughout these 20 years of practice. Although most variabl...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039691/ https://www.ncbi.nlm.nih.gov/pubmed/32104207 http://dx.doi.org/10.3332/ecancer.2020.1005 |
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author | Maiz, Cristóbal Silva, Fernando Domínguez, Francisco Galindo, Héctor Camus, Mauricio León, Augusto Oddó, David Villarroel, Alejandra Razmilic, Dravna Navarro, María Elena Medina, Lidia Merino, Tomás Vines, Eugenio Peña, José Maldonado, Daniela Pinto, Mauricio P. Acevedo, Francisco Sánchez, César |
author_facet | Maiz, Cristóbal Silva, Fernando Domínguez, Francisco Galindo, Héctor Camus, Mauricio León, Augusto Oddó, David Villarroel, Alejandra Razmilic, Dravna Navarro, María Elena Medina, Lidia Merino, Tomás Vines, Eugenio Peña, José Maldonado, Daniela Pinto, Mauricio P. Acevedo, Francisco Sánchez, César |
author_sort | Maiz, Cristóbal |
collection | PubMed |
description | Breast cancer (BC) is the most common malignancy in women. We retrieved medical records from >2,000 Chilean BC patients over the 1997–2018 period. The objective was to assess changes in clinical presentation or prognosis of our patients throughout these 20 years of practice. Although most variables did not display significant variations, we observed a progressive increase in stage IV BC over this period. Our data showed that tumour stage III/IV or HER2-enriched subtype tumours were associated with poorer prognosis. In contrast, we found that patients diagnosed by mammography had better overall survival. We speculate that better screenings and more sensitive imaging could explain the unexpected rise in stage IV cases. Our results support mammography screenings as an effective measure to reduce BC-related mortality. |
format | Online Article Text |
id | pubmed-7039691 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cancer Intelligence |
record_format | MEDLINE/PubMed |
spelling | pubmed-70396912020-02-26 Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution Maiz, Cristóbal Silva, Fernando Domínguez, Francisco Galindo, Héctor Camus, Mauricio León, Augusto Oddó, David Villarroel, Alejandra Razmilic, Dravna Navarro, María Elena Medina, Lidia Merino, Tomás Vines, Eugenio Peña, José Maldonado, Daniela Pinto, Mauricio P. Acevedo, Francisco Sánchez, César Ecancermedicalscience Short Communication Breast cancer (BC) is the most common malignancy in women. We retrieved medical records from >2,000 Chilean BC patients over the 1997–2018 period. The objective was to assess changes in clinical presentation or prognosis of our patients throughout these 20 years of practice. Although most variables did not display significant variations, we observed a progressive increase in stage IV BC over this period. Our data showed that tumour stage III/IV or HER2-enriched subtype tumours were associated with poorer prognosis. In contrast, we found that patients diagnosed by mammography had better overall survival. We speculate that better screenings and more sensitive imaging could explain the unexpected rise in stage IV cases. Our results support mammography screenings as an effective measure to reduce BC-related mortality. Cancer Intelligence 2020-01-23 /pmc/articles/PMC7039691/ /pubmed/32104207 http://dx.doi.org/10.3332/ecancer.2020.1005 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Communication Maiz, Cristóbal Silva, Fernando Domínguez, Francisco Galindo, Héctor Camus, Mauricio León, Augusto Oddó, David Villarroel, Alejandra Razmilic, Dravna Navarro, María Elena Medina, Lidia Merino, Tomás Vines, Eugenio Peña, José Maldonado, Daniela Pinto, Mauricio P. Acevedo, Francisco Sánchez, César Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution |
title | Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution |
title_full | Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution |
title_fullStr | Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution |
title_full_unstemmed | Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution |
title_short | Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution |
title_sort | mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a university health institution |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039691/ https://www.ncbi.nlm.nih.gov/pubmed/32104207 http://dx.doi.org/10.3332/ecancer.2020.1005 |
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