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Single-cell RNA-sequencing identifies the developmental trajectory of C-Myc-dependent NK1.1(−) T-bet(+) intraepithelial lymphocyte precursors
Natural intraepithelial lymphocytes (IELs) are thymus-derived adaptive immune cells, which are important contributors to intestinal immune homeostasis. Similar to other innate-like T cells, they are induced in the thymus through high-avidity interaction that would otherwise lead to clonal deletion i...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039806/ https://www.ncbi.nlm.nih.gov/pubmed/31712600 http://dx.doi.org/10.1038/s41385-019-0220-y |