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Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leucocyte antigen locus

Invasive group A streptococcal (GAS) disease is uncommon but carries a high case-fatality rate relative to other infectious diseases. Given the ubiquity of mild GAS infections, it remains unclear why healthy individuals will occasionally develop life-threatening infections, raising the possibility o...

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Detalles Bibliográficos
Autores principales:	Parks, Tom, Elliott, Katherine, Lamagni, Theresa, Auckland, Kathryn, Mentzer, Alexander J., Guy, Rebecca, Cartledge, Doreen, Strakova, Lenka, Connor, Daniel O’, Pollard, Andrew J., Neville, Matthew J., Mahajan, Anubha, Ashrafian, Houman, Chapman, Stephen J., Hill, Adrian V. S., Sriskandan, Shiranee, Knight, Julian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039814/ https://www.ncbi.nlm.nih.gov/pubmed/31462703 http://dx.doi.org/10.1038/s41435-019-0082-z

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