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Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

Seipin deficiency causes severe congenital generalized lipodystrophy (CGL) and metabolic disease. However, how seipin regulates adipocyte development and function remains incompletely understood. We previously showed that seipin acts as a scaffold protein for AGPAT2, whose disruption also causes CGL...

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Detalles Bibliográficos
Autores principales:	Sim, M. F. Michelle, Persiani, Elisa, Talukder, Md. Mesbah Uddin, Mcilroy, George D., Roumane, Ahlima, Edwardson, J. Michael, Rochford, Justin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039881/ https://www.ncbi.nlm.nih.gov/pubmed/32094408 http://dx.doi.org/10.1038/s41598-020-59982-5

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