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A novelty-retrieval-extinction paradigm leads to persistent attenuation of remote fear memories
Exposure to a novel environment can enhance the extinction of recent contextual fear in mice. This has been explained by a tagging and capture hypothesis. Consistently, we show in mice that exposure to a novel environment before extinction training promoted the extinction of recent auditory fear. Ho...
Autores principales: | Huang, Fulian, Zou, Guangjing, Li, Can, Meng, Hui, Liu, Xiaoyan, Yang, Zehua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039928/ https://www.ncbi.nlm.nih.gov/pubmed/32094477 http://dx.doi.org/10.1038/s41598-020-60176-2 |
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