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Pan-cancer mapping of differential protein-protein interactions

Deciphering the variations in the protein interactome is required to reach a systems-level understanding of tumorigenesis. To accomplish this task, we have considered the clinical and transcriptome data on >6000 samples from The Cancer Genome Atlas for 12 different cancers. Utilizing the gene exp...

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Detalles Bibliográficos
Autores principales: Gulfidan, Gizem, Turanli, Beste, Beklen, Hande, Sinha, Raghu, Arga, Kazim Yalcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039988/
https://www.ncbi.nlm.nih.gov/pubmed/32094374
http://dx.doi.org/10.1038/s41598-020-60127-x