Innate T-αβ lymphocytes as new immunological components of anti-tumoral “off-target” effects of the tyrosine kinase inhibitor dasatinib

Kinase inhibitors hold great potential as targeted therapy against malignant cells. Among them, the tyrosine kinase inhibitor dasatinib is known for a number of clinically relevant off-target actions, attributed in part to effects on components of the immune system, especially conventional T-cells a...

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Detalles Bibliográficos
Autores principales: Barbarin, Alice, Abdallah, Myriam, Lefèvre, Lucie, Piccirilli, Nathalie, Cayssials, Emilie, Roy, Lydia, Gombert, Jean-Marc, Herbelin, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039999/
https://www.ncbi.nlm.nih.gov/pubmed/32094501
http://dx.doi.org/10.1038/s41598-020-60195-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039999/
https://www.ncbi.nlm.nih.gov/pubmed/32094501
http://dx.doi.org/10.1038/s41598-020-60195-z

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