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Innate T-αβ lymphocytes as new immunological components of anti-tumoral “off-target” effects of the tyrosine kinase inhibitor dasatinib
Kinase inhibitors hold great potential as targeted therapy against malignant cells. Among them, the tyrosine kinase inhibitor dasatinib is known for a number of clinically relevant off-target actions, attributed in part to effects on components of the immune system, especially conventional T-cells a...
Autores principales: | Barbarin, Alice, Abdallah, Myriam, Lefèvre, Lucie, Piccirilli, Nathalie, Cayssials, Emilie, Roy, Lydia, Gombert, Jean-Marc, Herbelin, André |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039999/ https://www.ncbi.nlm.nih.gov/pubmed/32094501 http://dx.doi.org/10.1038/s41598-020-60195-z |
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