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In silico Strategies to Support Fragment-to-Lead Optimization in Drug Discovery

Fragment-based drug (or lead) discovery (FBDD or FBLD) has developed in the last two decades to become a successful key technology in the pharmaceutical industry for early stage drug discovery and development. The FBDD strategy consists of screening low molecular weight compounds against macromolecu...

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Detalles Bibliográficos
Autores principales:	de Souza Neto, Lauro Ribeiro, Moreira-Filho, José Teófilo, Neves, Bruno Junior, Maidana, Rocío Lucía Beatriz Riveros, Guimarães, Ana Carolina Ramos, Furnham, Nicholas, Andrade, Carolina Horta, Silva, Floriano Paes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040036/ https://www.ncbi.nlm.nih.gov/pubmed/32133344 http://dx.doi.org/10.3389/fchem.2020.00093

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