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Knocking Out SST Gene of BGC823 Gastric Cancer Cell by CRISPR/Cas9 Enhances Migration, Invasion and Expression of SEMA5A and KLF2

BACKGROUND: The impact and potential molecular mechanisms of SST in the occurrence and development of GC have not been determined. MATERIALS AND METHODS: Two pairs of sgRNA and reporter were designed according to targeting sequence of SST gene for double-nicking. Plasmids were transfected into 293T...

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Detalles Bibliográficos
Autores principales:	Chen, Wei, Ding, Ruixian, Tang, Jinlu, Li, Haodong, Chen, Chonghua, Zhang, Yaru, Zhang, Qinxian, Zhu, Xiaoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040191/ https://www.ncbi.nlm.nih.gov/pubmed/32110105 http://dx.doi.org/10.2147/CMAR.S236374

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