Cargando…

The role of elastography in the assessment of chronic liver disease in children

BACKGROUND: Conventional ultrasonography is a method preferred for the investigation of chronic liver diseases in pediatric groups, as it is non-invasive, cheap, feasible and available. The purpose of this study is to present the role of Share-wave Elastography (SWE) in terms of diagnostic value in...

Descripción completa

Detalles Bibliográficos
Autores principales: Sönmez, Süleyman, Boşat, Merve, Yurtseven, Nihal, Yurtseven, Eray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040250/
https://www.ncbi.nlm.nih.gov/pubmed/32127854
http://dx.doi.org/10.4314/ahs.v19i3.57
_version_ 1783500945527668736
author Sönmez, Süleyman
Boşat, Merve
Yurtseven, Nihal
Yurtseven, Eray
author_facet Sönmez, Süleyman
Boşat, Merve
Yurtseven, Nihal
Yurtseven, Eray
author_sort Sönmez, Süleyman
collection PubMed
description BACKGROUND: Conventional ultrasonography is a method preferred for the investigation of chronic liver diseases in pediatric groups, as it is non-invasive, cheap, feasible and available. The purpose of this study is to present the role of Share-wave Elastography (SWE) in terms of diagnostic value in children diagnosed with “chronic liver disease.” METHODS: We studied patients who had been diagnosed with chronic liver disease between March 2012-September 2015, and who had undergone liver biopsy and had their pathology results, compared with 26 healthy subjects. Statistical analysis was performed with IBM SPSS Statistics for Windows, Version 20.0. “Pearson Correlation Analysis” was performed in order to measure the relationship between elastography values and Brunt level. RESULTS: This study had 107 subjects in total, consisting of 81 patients between 0–204 months of age Pearson correlation coefficient level was determined as r = 0.644. Since the correlation coefficient is positive, there is a same-directional relationship between Elastography level and Brunt degree. This means that while one of the variables is increasing, the other one will also increase. CONCLUSION: Since it is known that development of hepatic fibrosis is a dynamic process, and that many hepatic fibrosis etiologies are known to continue throughout the course of life, the application of Real time SWE method instead of repeated liver biopsies on patients is a much simpler and smart method. Increasing the clinical use of Real Time SWE method with future studies might provide an opportunity for preventing unnecessary liver biopsies since the patients are evaluated in a shorter time and in a cost-effective manner.
format Online
Article
Text
id pubmed-7040250
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Makerere Medical School
record_format MEDLINE/PubMed
spelling pubmed-70402502020-03-03 The role of elastography in the assessment of chronic liver disease in children Sönmez, Süleyman Boşat, Merve Yurtseven, Nihal Yurtseven, Eray Afr Health Sci Articles BACKGROUND: Conventional ultrasonography is a method preferred for the investigation of chronic liver diseases in pediatric groups, as it is non-invasive, cheap, feasible and available. The purpose of this study is to present the role of Share-wave Elastography (SWE) in terms of diagnostic value in children diagnosed with “chronic liver disease.” METHODS: We studied patients who had been diagnosed with chronic liver disease between March 2012-September 2015, and who had undergone liver biopsy and had their pathology results, compared with 26 healthy subjects. Statistical analysis was performed with IBM SPSS Statistics for Windows, Version 20.0. “Pearson Correlation Analysis” was performed in order to measure the relationship between elastography values and Brunt level. RESULTS: This study had 107 subjects in total, consisting of 81 patients between 0–204 months of age Pearson correlation coefficient level was determined as r = 0.644. Since the correlation coefficient is positive, there is a same-directional relationship between Elastography level and Brunt degree. This means that while one of the variables is increasing, the other one will also increase. CONCLUSION: Since it is known that development of hepatic fibrosis is a dynamic process, and that many hepatic fibrosis etiologies are known to continue throughout the course of life, the application of Real time SWE method instead of repeated liver biopsies on patients is a much simpler and smart method. Increasing the clinical use of Real Time SWE method with future studies might provide an opportunity for preventing unnecessary liver biopsies since the patients are evaluated in a shorter time and in a cost-effective manner. Makerere Medical School 2019-09 /pmc/articles/PMC7040250/ /pubmed/32127854 http://dx.doi.org/10.4314/ahs.v19i3.57 Text en © 2019 Sönmez et al. Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Sönmez, Süleyman
Boşat, Merve
Yurtseven, Nihal
Yurtseven, Eray
The role of elastography in the assessment of chronic liver disease in children
title The role of elastography in the assessment of chronic liver disease in children
title_full The role of elastography in the assessment of chronic liver disease in children
title_fullStr The role of elastography in the assessment of chronic liver disease in children
title_full_unstemmed The role of elastography in the assessment of chronic liver disease in children
title_short The role of elastography in the assessment of chronic liver disease in children
title_sort role of elastography in the assessment of chronic liver disease in children
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040250/
https://www.ncbi.nlm.nih.gov/pubmed/32127854
http://dx.doi.org/10.4314/ahs.v19i3.57
work_keys_str_mv AT sonmezsuleyman theroleofelastographyintheassessmentofchronicliverdiseaseinchildren
AT bosatmerve theroleofelastographyintheassessmentofchronicliverdiseaseinchildren
AT yurtsevennihal theroleofelastographyintheassessmentofchronicliverdiseaseinchildren
AT yurtseveneray theroleofelastographyintheassessmentofchronicliverdiseaseinchildren
AT sonmezsuleyman roleofelastographyintheassessmentofchronicliverdiseaseinchildren
AT bosatmerve roleofelastographyintheassessmentofchronicliverdiseaseinchildren
AT yurtsevennihal roleofelastographyintheassessmentofchronicliverdiseaseinchildren
AT yurtseveneray roleofelastographyintheassessmentofchronicliverdiseaseinchildren