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The role of elastography in the assessment of chronic liver disease in children
BACKGROUND: Conventional ultrasonography is a method preferred for the investigation of chronic liver diseases in pediatric groups, as it is non-invasive, cheap, feasible and available. The purpose of this study is to present the role of Share-wave Elastography (SWE) in terms of diagnostic value in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Makerere Medical School
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040250/ https://www.ncbi.nlm.nih.gov/pubmed/32127854 http://dx.doi.org/10.4314/ahs.v19i3.57 |
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author | Sönmez, Süleyman Boşat, Merve Yurtseven, Nihal Yurtseven, Eray |
author_facet | Sönmez, Süleyman Boşat, Merve Yurtseven, Nihal Yurtseven, Eray |
author_sort | Sönmez, Süleyman |
collection | PubMed |
description | BACKGROUND: Conventional ultrasonography is a method preferred for the investigation of chronic liver diseases in pediatric groups, as it is non-invasive, cheap, feasible and available. The purpose of this study is to present the role of Share-wave Elastography (SWE) in terms of diagnostic value in children diagnosed with “chronic liver disease.” METHODS: We studied patients who had been diagnosed with chronic liver disease between March 2012-September 2015, and who had undergone liver biopsy and had their pathology results, compared with 26 healthy subjects. Statistical analysis was performed with IBM SPSS Statistics for Windows, Version 20.0. “Pearson Correlation Analysis” was performed in order to measure the relationship between elastography values and Brunt level. RESULTS: This study had 107 subjects in total, consisting of 81 patients between 0–204 months of age Pearson correlation coefficient level was determined as r = 0.644. Since the correlation coefficient is positive, there is a same-directional relationship between Elastography level and Brunt degree. This means that while one of the variables is increasing, the other one will also increase. CONCLUSION: Since it is known that development of hepatic fibrosis is a dynamic process, and that many hepatic fibrosis etiologies are known to continue throughout the course of life, the application of Real time SWE method instead of repeated liver biopsies on patients is a much simpler and smart method. Increasing the clinical use of Real Time SWE method with future studies might provide an opportunity for preventing unnecessary liver biopsies since the patients are evaluated in a shorter time and in a cost-effective manner. |
format | Online Article Text |
id | pubmed-7040250 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Makerere Medical School |
record_format | MEDLINE/PubMed |
spelling | pubmed-70402502020-03-03 The role of elastography in the assessment of chronic liver disease in children Sönmez, Süleyman Boşat, Merve Yurtseven, Nihal Yurtseven, Eray Afr Health Sci Articles BACKGROUND: Conventional ultrasonography is a method preferred for the investigation of chronic liver diseases in pediatric groups, as it is non-invasive, cheap, feasible and available. The purpose of this study is to present the role of Share-wave Elastography (SWE) in terms of diagnostic value in children diagnosed with “chronic liver disease.” METHODS: We studied patients who had been diagnosed with chronic liver disease between March 2012-September 2015, and who had undergone liver biopsy and had their pathology results, compared with 26 healthy subjects. Statistical analysis was performed with IBM SPSS Statistics for Windows, Version 20.0. “Pearson Correlation Analysis” was performed in order to measure the relationship between elastography values and Brunt level. RESULTS: This study had 107 subjects in total, consisting of 81 patients between 0–204 months of age Pearson correlation coefficient level was determined as r = 0.644. Since the correlation coefficient is positive, there is a same-directional relationship between Elastography level and Brunt degree. This means that while one of the variables is increasing, the other one will also increase. CONCLUSION: Since it is known that development of hepatic fibrosis is a dynamic process, and that many hepatic fibrosis etiologies are known to continue throughout the course of life, the application of Real time SWE method instead of repeated liver biopsies on patients is a much simpler and smart method. Increasing the clinical use of Real Time SWE method with future studies might provide an opportunity for preventing unnecessary liver biopsies since the patients are evaluated in a shorter time and in a cost-effective manner. Makerere Medical School 2019-09 /pmc/articles/PMC7040250/ /pubmed/32127854 http://dx.doi.org/10.4314/ahs.v19i3.57 Text en © 2019 Sönmez et al. Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Sönmez, Süleyman Boşat, Merve Yurtseven, Nihal Yurtseven, Eray The role of elastography in the assessment of chronic liver disease in children |
title | The role of elastography in the assessment of chronic liver disease in children |
title_full | The role of elastography in the assessment of chronic liver disease in children |
title_fullStr | The role of elastography in the assessment of chronic liver disease in children |
title_full_unstemmed | The role of elastography in the assessment of chronic liver disease in children |
title_short | The role of elastography in the assessment of chronic liver disease in children |
title_sort | role of elastography in the assessment of chronic liver disease in children |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040250/ https://www.ncbi.nlm.nih.gov/pubmed/32127854 http://dx.doi.org/10.4314/ahs.v19i3.57 |
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