Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma

Targeted therapy for kidney cancer has achieved significant clinical results. However, because most patients who use targeted therapy will develop drug resistance, we still need to constantly explore new therapeutic targets. Although porcupine (PORCN) as a palmitoyltransferase plays a crucial role i...

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Detalles Bibliográficos
Autores principales: Li, Jianyi, Wu, Guangzhen, Xu, Yingkun, Li, Jiatong, Ruan, Ningke, Chen, Yougen, Zhang, Qi, Xia, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040395/
https://www.ncbi.nlm.nih.gov/pubmed/32104684
http://dx.doi.org/10.1155/2020/2527643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040395/
https://www.ncbi.nlm.nih.gov/pubmed/32104684
http://dx.doi.org/10.1155/2020/2527643

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