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The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus
Kidney involvement is frequent in patients with systemic lupus erythematosus (SLE), although it may not be present from disease onset. Renal lupus itself is highly heterogenous with respect to the combination and/or severity of clinical and/or laboratory manifestations. This is a case of a 45-year-o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040396/ https://www.ncbi.nlm.nih.gov/pubmed/32099705 http://dx.doi.org/10.1155/2020/7869216 |
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author | Lionaki, Sophia Liapis, George Vallianou, Kalliope Vergadis, Chrysovalantis Boletis, Ioannis |
author_facet | Lionaki, Sophia Liapis, George Vallianou, Kalliope Vergadis, Chrysovalantis Boletis, Ioannis |
author_sort | Lionaki, Sophia |
collection | PubMed |
description | Kidney involvement is frequent in patients with systemic lupus erythematosus (SLE), although it may not be present from disease onset. Renal lupus itself is highly heterogenous with respect to the combination and/or severity of clinical and/or laboratory manifestations. This is a case of a 45-year-old Caucasian female with an established diagnosis of SLE, who presented four times with new onset of proteinuria during a follow-up time of ten years, since the diagnosis of SLE. Specifically, she experienced two episodes of lupus membranous nephropathy, and after she achieved remission, she developed twice overt nephrotic syndrome associated with new and biopsy proven lupus podocytopathy. All these episodes of nephrotic syndrome were combined with systemic symptoms, attributed to lupus itself, while serological activity of lupus was also noted. This case highlights the importance of performing a kidney biopsy in all patients with SLE who have new renal manifestations, including nephrotic proteinuria. |
format | Online Article Text |
id | pubmed-7040396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-70403962020-02-25 The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus Lionaki, Sophia Liapis, George Vallianou, Kalliope Vergadis, Chrysovalantis Boletis, Ioannis Case Rep Nephrol Case Report Kidney involvement is frequent in patients with systemic lupus erythematosus (SLE), although it may not be present from disease onset. Renal lupus itself is highly heterogenous with respect to the combination and/or severity of clinical and/or laboratory manifestations. This is a case of a 45-year-old Caucasian female with an established diagnosis of SLE, who presented four times with new onset of proteinuria during a follow-up time of ten years, since the diagnosis of SLE. Specifically, she experienced two episodes of lupus membranous nephropathy, and after she achieved remission, she developed twice overt nephrotic syndrome associated with new and biopsy proven lupus podocytopathy. All these episodes of nephrotic syndrome were combined with systemic symptoms, attributed to lupus itself, while serological activity of lupus was also noted. This case highlights the importance of performing a kidney biopsy in all patients with SLE who have new renal manifestations, including nephrotic proteinuria. Hindawi 2020-02-13 /pmc/articles/PMC7040396/ /pubmed/32099705 http://dx.doi.org/10.1155/2020/7869216 Text en Copyright © 2020 Sophia Lionaki et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lionaki, Sophia Liapis, George Vallianou, Kalliope Vergadis, Chrysovalantis Boletis, Ioannis The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
title | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
title_full | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
title_fullStr | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
title_full_unstemmed | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
title_short | The Various Forms of Nephrotic Syndrome in a Patient with Systemic Lupus Erythematosus |
title_sort | various forms of nephrotic syndrome in a patient with systemic lupus erythematosus |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040396/ https://www.ncbi.nlm.nih.gov/pubmed/32099705 http://dx.doi.org/10.1155/2020/7869216 |
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