A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer's Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3

Oxidative stress-induced mitochondrial dysfunction and cell senescence are considered critical contributors to Alzheimer's disease (AD), and oxidant/antioxidant imbalance has been a therapeutic target in AD. SIRT3 is a mitochondrial protein regulating metabolic enzyme activity by deacetylation...

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Detalles Bibliográficos
Autores principales: Li, Yi, Lu, Jing, Cao, Xin, Zhao, Hongwei, Gao, Longfei, Xia, Peng, Pei, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040408/
https://www.ncbi.nlm.nih.gov/pubmed/32104538
http://dx.doi.org/10.1155/2020/7698560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040408/
https://www.ncbi.nlm.nih.gov/pubmed/32104538
http://dx.doi.org/10.1155/2020/7698560

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