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A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer's Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3

Oxidative stress-induced mitochondrial dysfunction and cell senescence are considered critical contributors to Alzheimer's disease (AD), and oxidant/antioxidant imbalance has been a therapeutic target in AD. SIRT3 is a mitochondrial protein regulating metabolic enzyme activity by deacetylation...

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Detalles Bibliográficos
Autores principales:	Li, Yi, Lu, Jing, Cao, Xin, Zhao, Hongwei, Gao, Longfei, Xia, Peng, Pei, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040408/ https://www.ncbi.nlm.nih.gov/pubmed/32104538 http://dx.doi.org/10.1155/2020/7698560

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