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Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish

Sexual differences have been observed in the onset and prognosis of human cardiovascular diseases, but the underlying mechanisms are not clear. Here, we found that zebrafish heart regeneration is faster in females, can be accelerated by estrogen and is suppressed by the estrogen-antagonist tamoxifen...

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Detalles Bibliográficos
Autores principales: Xu, Shisan, Xie, Fangjing, Tian, Li, Fallah, Samane, Babaei, Fatemeh, Manno, Sinai H C, Manno, Francis A M, Zhu, Lina, Wong, Kin Fung, Liang, Yimin, Ramalingam, Rajkumar, Sun, Lei, Wang, Xin, Plumb, Robert, Gethings, Lee, Lam, Yun Wah, Cheng, Shuk Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040496/
https://www.ncbi.nlm.nih.gov/pubmed/31977314
http://dx.doi.org/10.1530/JOE-19-0413