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Impaired platelet‐dependent thrombin generation associated with thrombocytopenia is improved by prothrombin complex concentrates in vitro
BACKGROUND: Impaired thrombin generation (TG) in patients with acquired coagulopathy, is due to low coagulation factors and thrombocytopenia. The latter is typically treated with platelet transfusions and the former with plasma and occasionally with prothrombin complex concentrates (PCCs). We hypoth...
Autores principales: | Chowdary, Pratima, Hamid, Colleen, Slatter, David, Morris, Richard, Foley, Jonathan H., Gomez, Keith, Brodkin, Edgar, Fox, Thomas A., Gatt, Alex, McVey, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040546/ https://www.ncbi.nlm.nih.gov/pubmed/32110765 http://dx.doi.org/10.1002/rth2.12310 |
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