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Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems
Today, dendrimers are the main nanoparticle applied to drug delivery systems. The physicochemical characteristics of dendrimers and their versatility structural modification make them attractive to applied as a platform to bioactive molecules transport. Nanoformulations based on dendrimers enhance l...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040653/ https://www.ncbi.nlm.nih.gov/pubmed/31991703 http://dx.doi.org/10.3390/ma13030570 |
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author | Sandoval-Yañez, Claudia Castro Rodriguez, Cristian |
author_facet | Sandoval-Yañez, Claudia Castro Rodriguez, Cristian |
author_sort | Sandoval-Yañez, Claudia |
collection | PubMed |
description | Today, dendrimers are the main nanoparticle applied to drug delivery systems. The physicochemical characteristics of dendrimers and their versatility structural modification make them attractive to applied as a platform to bioactive molecules transport. Nanoformulations based on dendrimers enhance low solubility drugs, arrival to the target tissue, drugs bioavailability, and controlled release. This review describes the latter approaches on the transport of bioactive molecules based on dendrimers. The review focus is on the last therapeutic strategies addressed by dendrimers conjugated with bioactive molecules. A brief review of the latest studies in therapies against cancer and cardiovascular diseases, as well as future projections in the area, are addressed. |
format | Online Article Text |
id | pubmed-7040653 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70406532020-03-09 Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems Sandoval-Yañez, Claudia Castro Rodriguez, Cristian Materials (Basel) Review Today, dendrimers are the main nanoparticle applied to drug delivery systems. The physicochemical characteristics of dendrimers and their versatility structural modification make them attractive to applied as a platform to bioactive molecules transport. Nanoformulations based on dendrimers enhance low solubility drugs, arrival to the target tissue, drugs bioavailability, and controlled release. This review describes the latter approaches on the transport of bioactive molecules based on dendrimers. The review focus is on the last therapeutic strategies addressed by dendrimers conjugated with bioactive molecules. A brief review of the latest studies in therapies against cancer and cardiovascular diseases, as well as future projections in the area, are addressed. MDPI 2020-01-24 /pmc/articles/PMC7040653/ /pubmed/31991703 http://dx.doi.org/10.3390/ma13030570 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sandoval-Yañez, Claudia Castro Rodriguez, Cristian Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems |
title | Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems |
title_full | Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems |
title_fullStr | Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems |
title_full_unstemmed | Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems |
title_short | Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems |
title_sort | dendrimers: amazing platforms for bioactive molecule delivery systems |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040653/ https://www.ncbi.nlm.nih.gov/pubmed/31991703 http://dx.doi.org/10.3390/ma13030570 |
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