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Pre- and post-sequencing recommendations for functional annotation of human fecal metagenomes

BACKGROUND: Shotgun metagenomes are often assembled prior to annotation of genes which biases the functional capacity of a community towards its most abundant members. For an unbiased assessment of community function, short reads need to be mapped directly to a gene or protein database. The ability...

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Detalles Bibliográficos
Autores principales: Treiber, Michelle L., Taft, Diana H., Korf, Ian, Mills, David A., Lemay, Danielle G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041091/
https://www.ncbi.nlm.nih.gov/pubmed/32093654
http://dx.doi.org/10.1186/s12859-020-3416-y