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Linked optical and gene expression profiling of single cells at high-throughput

Single-cell RNA sequencing has emerged as a powerful tool for characterizing cells, but not all phenotypes of interest can be observed through changes in gene expression. Linking sequencing with optical analysis has provided insight into the molecular basis of cellular function, but current approach...

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Detalles Bibliográficos
Autores principales: Zhang, Jesse Q., Siltanen, Christian A., Liu, Leqian, Chang, Kai-Chun, Gartner, Zev J., Abate, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041248/
https://www.ncbi.nlm.nih.gov/pubmed/32093753
http://dx.doi.org/10.1186/s13059-020-01958-9