Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation

Renal cell carcinoma with sarcomatoid features is a rare presentation with a 5% incidence. Sarcomatoid renal cell carcinoma is usually associated with poor prognosis. It commonly metastasizes to the lungs, bones, and liver. Dermatological manifestation with paraneoplastic syndrome is extremely rare....

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Autores principales: Gupta, Amit, Gupta, Ashish, Gupta, Sweety, Durgapal, Prashant, Ravi, Bina, Sideek, Rohik Anjum T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041359/
https://www.ncbi.nlm.nih.gov/pubmed/32165843
http://dx.doi.org/10.4103/njs.NJS_4_19
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author Gupta, Amit
Gupta, Ashish
Gupta, Sweety
Durgapal, Prashant
Ravi, Bina
Sideek, Rohik Anjum T
author_facet Gupta, Amit
Gupta, Ashish
Gupta, Sweety
Durgapal, Prashant
Ravi, Bina
Sideek, Rohik Anjum T
author_sort Gupta, Amit
collection PubMed
description Renal cell carcinoma with sarcomatoid features is a rare presentation with a 5% incidence. Sarcomatoid renal cell carcinoma is usually associated with poor prognosis. It commonly metastasizes to the lungs, bones, and liver. Dermatological manifestation with paraneoplastic syndrome is extremely rare. Pathogenesis of PNP in renal cell carcinoma is not cleat; till date, however, few literature suggest antibodies against a group plakin family which plays a key role in intermediate filament attachment in RCC. We present PNP in a 64-year-old female associated with renal cell carcinoma.
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spelling pubmed-70413592020-03-12 Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation Gupta, Amit Gupta, Ashish Gupta, Sweety Durgapal, Prashant Ravi, Bina Sideek, Rohik Anjum T Niger J Surg Case Report Renal cell carcinoma with sarcomatoid features is a rare presentation with a 5% incidence. Sarcomatoid renal cell carcinoma is usually associated with poor prognosis. It commonly metastasizes to the lungs, bones, and liver. Dermatological manifestation with paraneoplastic syndrome is extremely rare. Pathogenesis of PNP in renal cell carcinoma is not cleat; till date, however, few literature suggest antibodies against a group plakin family which plays a key role in intermediate filament attachment in RCC. We present PNP in a 64-year-old female associated with renal cell carcinoma. Wolters Kluwer - Medknow 2020 2020-02-10 /pmc/articles/PMC7041359/ /pubmed/32165843 http://dx.doi.org/10.4103/njs.NJS_4_19 Text en Copyright: © 2020 Nigerian Journal of Surgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gupta, Amit
Gupta, Ashish
Gupta, Sweety
Durgapal, Prashant
Ravi, Bina
Sideek, Rohik Anjum T
Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation
title Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation
title_full Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation
title_fullStr Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation
title_full_unstemmed Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation
title_short Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation
title_sort pemphigus in sarcomatoid renal cell carcinoma: a rare paraneoplastic manifestation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041359/
https://www.ncbi.nlm.nih.gov/pubmed/32165843
http://dx.doi.org/10.4103/njs.NJS_4_19
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