Cargando…

Tumor Targeted Curcumin Delivery by Folate-Modified MPEG-PCL Self-Assembly Micelles for Colorectal Cancer Therapy

INTRODUCTION: Curcumin (Cur) is a natural extract of Asian spice Curcumin longa, showing multi-targeting capability and low toxicity in anti-tumor activities. The low bioavailability restricts its application as a therapeutic agent. Folate (FA) receptors are highly expressed in many malignant tumors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Yuzhu, He, Yihong, Ji, Jianrui, Zheng, Songping, Cheng, Yongzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041608/ https://www.ncbi.nlm.nih.gov/pubmed/32110020 http://dx.doi.org/10.2147/IJN.S232777

Ejemplares similares

Self-assembled mPEG–PCL-g–PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro
por: Shi, Shuai, et al.
Publicado: (2012)

Poly(ε-Caprolactone)-Methoxypolyethylene Glycol (PCL-MPEG)-Based Micelles for Drug-Delivery: The Effect of PCL Chain Length on Blood Components, Phagocytosis, and Biodistribution
por: Hou, Zemin, et al.
Publicado: (2022)

Combined Shikonin-Loaded MPEG-PCL Micelles Inhibits Effective Transition of Endothelial-to-Mesenchymal Cells
por: Li, Guanglin, et al.
Publicado: (2022)

Micellar emulsions composed of mPEG-PCL/MCT as novel nanocarriers for systemic delivery of genistein: a comparative study with micelles
por: Zhang, Tianpeng, et al.
Publicado: (2015)

Enhanced Anticancer Activity of 5’-DFUR-PCL-MPEG Polymeric Prodrug Micelles Encapsulating Chemotherapeutic Drugs
por: Sawdon, Alicia J., et al.
Publicado: (2018)

Mitochondria-targeted curcumin loaded CTPP–PEG–PCL self-assembled micelles for improving liver fibrosis therapy
por: Zhang, Liqiao, et al.
Publicado: (2021)

Self-assembled micelles based on pH-sensitive PAE-g-MPEG-cholesterol block copolymer for anticancer drug delivery
por: Zhang, Can Yang, et al.
Publicado: (2014)

Codelivery of curcumin and doxorubicin by MPEG-PCL results in improved efficacy of systemically administered chemotherapy in mice with lung cancer
por: Wang, Bi-Lan, et al.
Publicado: (2013)

Preparation, characterisation, and controlled release of sex pheromone-loaded MPEG-PCL diblock copolymer micelles for Spodoptera litura (Lepidoptera: Noctuidae)
por: Chen, Yixin, et al.
Publicado: (2018)

Preparation, characterization, and evaluation of amphotericin B-loaded MPEG-PCL-g-PEI micelles for local treatment of oral Candida albicans
por: Zhou, Li, et al.
Publicado: (2017)

Synthesis and self-assembly of curcumin-modified amphiphilic polymeric micelles with antibacterial activity
por: Barros, Caio H. N., et al.
Publicado: (2021)

Co-Delivery of Docetaxel and Curcumin via Nanomicelles for Enhancing Anti-Ovarian Cancer Treatment
por: Hu, Yuzhu, et al.
Publicado: (2020)

Preparation and evaluation of PCL-PEG-PCL micelles as potential nanocarriers for ocular delivery of dexamethasone
por: Alami-Milani, Mitra, et al.
Publicado: (2018)

Hyaluronic acid modified MPEG-b-PAE block copolymer aqueous micelles for efficient ophthalmic drug delivery of hydrophobic genistein
por: Li, Cong, et al.
Publicado: (2018)

The Osteogenesis of Bone Marrow Stem Cells on mPEG-PCL-mPEG/Hydroxyapatite Composite Scaffold via Solid Freeform Fabrication
por: Liao, Han-Tsung, et al.
Publicado: (2014)

A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting
por: Zhang, Lin, et al.
Publicado: (2012)

Synthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy
por: Xie, Jing, et al.
Publicado: (2016)

Alendronate modified mPEG-PLGA nano-micelle drug delivery system loaded with astragaloside has anti-osteoporotic effect in rats
por: Xi, Yanhai, et al.
Publicado: (2022)

Delivery of curcumin by directed self-assembled micelles enhances therapeutic treatment of non-small-cell lung cancer
por: Zhu, Wen-Ting, et al.
Publicado: (2017)

Surface modification of MPEG-b-PCL-based nanoparticles via oxidative self-polymerization of dopamine for malignant melanoma therapy
por: Xiong, Wei, et al.
Publicado: (2015)

Curcumin-Loaded Oil-Free Self-Assembled Micelles Inhibit the Influenza A Virus Activity and the Solidification of Curcumin-Loaded Micelles for Pharmaceutical Applications
por: Li, Cun-Zhao, et al.
Publicado: (2022)

ROS-sensitive calcipotriol nano-micelles prepared by methoxypolyethylene glycol (mPEG) – modified polymer for the treatment of psoriasis
por: Hua, Yulin, et al.
Publicado: (2022)

Biodegradable micelles enhance the antiglioma activity of curcumin in vitro and in vivo
por: Zheng, Songping, et al.
Publicado: (2016)

Tetracycline-grafted mPEG-PLGA micelles for bone-targeting and osteoporotic improvement
por: Que, Yunduan, et al.
Publicado: (2022)

Delivery of curcumin by directed self-assembled micelles enhances therapeutic treatment of non-small-cell lung cancer [Corrigendum]
Publicado: (2017)

Acetal-Linked Paclitaxel Polymeric Prodrug Based on Functionalized mPEG-PCL Diblock Polymer for pH-Triggered Drug Delivery
por: Zhai, Yinglei, et al.
Publicado: (2017)

The mPEG-PCL Copolymer for Selective Fermentation of Staphylococcus lugdunensis Against Candida parapsilosis in the Human Microbiome
por: Kao, Ming-Shan, et al.
Publicado: (2016)

pH-Sensitive Mixed Micelles Assembled from PDEAEMA-PPEGMA and PCL-PPEGMA for Doxorubicin Delivery: Experimental and DPD Simulations Study
por: Yang, Chufen, et al.
Publicado: (2020)

Curcumin-loaded redox response of self-assembled micelles for enhanced antitumor and anti-inflammation efficacy
por: Zhao, Shuang, et al.
Publicado: (2017)

Improving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG(2000) micelles
por: Cai, Lulu, et al.
Publicado: (2013)

mPEG-PDLLA Micelles Potentiate Docetaxel for Intraperitoneal Chemotherapy in Ovarian Cancer Peritoneal Metastasis
por: Zhang, Yumei, et al.
Publicado: (2022)

Folated Synperonic-Cholesteryl Hemisuccinate Polymeric Micelles for the Targeted Delivery of Docetaxel in Melanoma
por: Varshosaz, Jaleh, et al.
Publicado: (2015)

Self-assembled supramolecular hydrogel based on PCL-PEG-PCL triblock copolymer and γ-cyclodextrin inclusion complex for sustained delivery of dexamethasone
por: Khodaverdi, Elham, et al.
Publicado: (2016)

Targeted delivery by pH-responsive mPEG-S-PBLG micelles significantly enhances the anti-tumor efficacy of doxorubicin with reduced cardiotoxicity
por: Feng, Qiyi, et al.
Publicado: (2021)

Preparation, characterization and application of star-shaped PCL/PEG micelles for the delivery of doxorubicin in the treatment of colon cancer
por: Gao, Xiang, et al.
Publicado: (2013)

Efficient Self-Assembly of mPEG End-Capped Porous Silica as a Redox-Sensitive Nanocarrier for Controlled Doxorubicin Delivery
por: Nguyen, Anh Khoa, et al.
Publicado: (2018)

Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles
por: Feng, Runliang, et al.
Publicado: (2012)

mPEG-PLA/TPGS mixed micelles via intranasal administration improved the bioavailability of lamotrigine in the hippocampus
por: Yu, Anan, et al.
Publicado: (2017)

Effect of Formulation and Processing Parameters on the Size of mPEG-b-p(HPMA-Bz) Polymeric Micelles
por: Bagheri, Mahsa, et al.
Publicado: (2018)

pH-sensitive and folic acid-targeted MPEG-PHIS/FA-PEG-VE mixed micelles for the delivery of PTX-VE and their antitumor activity
por: Di, Yan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_aj546mp2klbjdf53eqtfvlpd1r