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Aurora A promotes chromosome congression by activating the condensin-dependent pool of KIF4A
Aurora kinases create phosphorylation gradients within the spindle during prometaphase and anaphase, thereby locally regulating factors that promote spindle organization, chromosome condensation and movement, and cytokinesis. We show that one such factor is the kinesin KIF4A, which is present along...
Autores principales: | Poser, Elena, Caous, Renaud, Gruneberg, Ulrike, Barr, Francis A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041678/ https://www.ncbi.nlm.nih.gov/pubmed/31881080 http://dx.doi.org/10.1083/jcb.201905194 |
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