Cargando…

Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase

The type II transmembrane serine protease Matriptase 1 (ST14) is commonly known as an oncogene, yet it also plays an understudied role in suppressing carcinogenesis. This double face is evident in the embryonic epidermis of zebrafish loss-of-function mutants in the cognate Matriptase inhibitor Hai1a...

Descripción completa

Detalles Bibliográficos
Autores principales: Armistead, Joy, Hatzold, Julia, van Roye, Anna, Fahle, Evelin, Hammerschmidt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041680/
https://www.ncbi.nlm.nih.gov/pubmed/31819976
http://dx.doi.org/10.1083/jcb.201905190