Cargando…
Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase
The type II transmembrane serine protease Matriptase 1 (ST14) is commonly known as an oncogene, yet it also plays an understudied role in suppressing carcinogenesis. This double face is evident in the embryonic epidermis of zebrafish loss-of-function mutants in the cognate Matriptase inhibitor Hai1a...
Autores principales: | Armistead, Joy, Hatzold, Julia, van Roye, Anna, Fahle, Evelin, Hammerschmidt, Matthias |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041680/ https://www.ncbi.nlm.nih.gov/pubmed/31819976 http://dx.doi.org/10.1083/jcb.201905190 |
Ejemplares similares
-
Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects
por: Hatzold, Julia, et al.
Publicado: (2023) -
Entosis Is Induced by Glucose Starvation
por: Hamann, Jens C., et al.
Publicado: (2017) -
Entosis is induced by ultraviolet radiation
por: Chen, Ruoyao, et al.
Publicado: (2021) -
Michael Overholtzer: Answering existential questions on entosis
por: Sedwick, Caitlin
Publicado: (2011) -
Entosis enables a population response to starvation
por: Hamann, Jens C., et al.
Publicado: (2017)