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Exocyst structural changes associated with activation of tethering downstream of Rho/Cdc42 GTPases

The exocyst complex plays a critical role in determining both temporal and spatial dynamics of exocytic vesicle tethering and fusion with the plasma membrane. However, the mechanism by which the exocyst functions and how it is regulated remain poorly understood. Here we describe a novel biochemical...

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Detalles Bibliográficos
Autores principales: Rossi, Guendalina, Lepore, Dante, Kenner, Lillian, Czuchra, Alexander B., Plooster, Melissa, Frost, Adam, Munson, Mary, Brennwald, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041683/
https://www.ncbi.nlm.nih.gov/pubmed/31904797
http://dx.doi.org/10.1083/jcb.201904161