Cargando…
Clathrin’s adaptor interaction sites are repurposed to stabilize microtubules during mitosis
Clathrin ensures mitotic spindle stability and efficient chromosome alignment, independently of its vesicle trafficking function. Although clathrin localizes to the mitotic spindle and kinetochore fiber microtubule bundles, the mechanisms by which clathrin stabilizes microtubules are unclear. We sho...
Autores principales: | Rondelet, Arnaud, Lin, Yu-Chih, Singh, Divya, Porfetye, Arthur T., Thakur, Harish C., Hecker, Andreas, Brinkert, Pia, Schmidt, Nadine, Bendre, Shweta, Müller, Franziska, Mazul, Lisa, Widlund, Per O., Bange, Tanja, Hiller, Michael, Vetter, Ingrid R., Bird, Alexander W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041688/ https://www.ncbi.nlm.nih.gov/pubmed/31932847 http://dx.doi.org/10.1083/jcb.201907083 |
Ejemplares similares
-
GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK
por: Bendre, Shweta, et al.
Publicado: (2016) -
Clathrin-Mediated Endocytosis and Adaptor Proteins
por: Popova, N.V., et al.
Publicado: (2013) -
Clathrin Is Spindle-Associated but Not Essential for Mitosis
por: Borlido, Joana, et al.
Publicado: (2008) -
In vivo phosphorylation of adaptors regulates their interaction with clathrin
Publicado: (1996) -
Clathrin binding by the adaptor Ent5 promotes late stages of clathrin coat maturation
por: Hung, Chao-Wei, et al.
Publicado: (2016)